A hydrating cream that visibly addresses the look of wrinkles and firmness that protects against free radicals*, Sisleÿa L'Intégral Anti-Âge Fresh Gel Cream is an incredible global solution that addresses the different causes of visible skin aging: genetic and epigenetic (i.e. linked to environmental and behavioral factors). It is these epigenetic factors that aid with visible skin aging. 1.6 oz. Made in France.